CHAPEL HILL, NC – A University of North Carolina at Chapel Hill spin-off company has been awarded a $2 million grant to commercialize a new technology to improve radiation treatment of prostate cancer.

The grant from the National Cancer Institute, as part of its Small Business Innovation Research program, will enable Morphormics Inc. to market its proprietary technology for rapidly constructing anatomical “roadmaps” of individual patients.

“These roadmaps are critical navigational aids that help physicians keep a radiation beam focused on the tumor, while at the same time avoiding nearby parts of the body that could be harmed by radiation exposure,” said Edward L. Chaney, Ph.D., Morphormics’ vice president of technology, professor in the School of Medicine’s department of radiation oncology.

Morphormics’ solution is based on “m-reps,” which are mathematical representations of anatomical structures. M-reps were conceived of and developed by UNC’s Medical Image Display and Analysis research group with federal funding. The

Morphormics system uses m-reps to automatically “extract” the prostate, bladder, seminal vesicles, a portion of the rectum and the femoral heads from 3-D medical images to form the anatomical roadmaps.

Morphormics, also known as Mx, was founded in 2001 by Chaney and fellow UNC professors Stephen M. Pizer, Ph.D., Kenan Professor in the departments of computer science and radiation oncology, and Sarang Joshi, D.Sc., who at the time was an assistant professor at UNC and is now at the University of Utah.

Morphormics’ formation was also facilitated by Nick England, president of 3rdTech, a business incubator company.

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